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Literature summary for 3.4.22.54 extracted from

  • de Morree, A.; Lutje Hulsik, D.; Impagliazzo, A.; van Haagen, H.H.; de Galan, P.; van Remoortere, A.; t Hoen, P.A.; van Ommen, G.B.; Frants, R.R.; van der Maarel, S.M.
    Calpain 3 is a rapid-action, unidirectional proteolytic switch central to muscle remodeling (2010), PLoS ONE, 5, e11940.
    View publication on PubMedView publication on EuropePMC

Protein Variants

Protein Variants Comment Organism
C129S inactive Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens calpain 3 does not cleave PIAS4 ?
-
?
PIAS3 + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
muscle
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AHNAK-N peptide + H2O a putative cleavage site is AHNAK-C2.2 Homo sapiens ?
-
?
additional information calpain 3 does not cleave PIAS4 Homo sapiens ?
-
?
PIAS3 + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
calpain 3
-
Homo sapiens
CAPN3
-
Homo sapiens