Literature summary for 3.4.22.54 extracted from

Tang, Y.; Liu, X.; Zoltoski, R.K.; Novak, L.A.; Herrera, R.A.; Richard, I.; Kuszak, J.R.; Kumar, N.M.
Age-related cataracts in alpha3Cx46-knockout mice are dependent on a calpain 3 isoform (2007), Invest. Ophthalmol. Vis. Sci., 48, 2685-2694.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lens	calpain 3 or its isoforms is necessary for formation of the nuclear cataract that is observed in the alpha3Cx46-/- lens. In the absence of the CAPN3 gene, the formation of a cataract is delayed, and its appearance is changed to a more diffuse, pulverulent type	Mus musculus	-

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Release 2023.1 (January 2023)