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Literature summary for 3.4.22.54 extracted from

  • Huang, Y.; de Morree, A.; van Remoortere, A.; Bushby, K.; Frants, R.R.; den Dunnen, J.; van der Maarel, S.M.
    Calpain 3 is a modulator of the dysferlin protein complex in skeletal muscle (2008), Hum. Mol. Genet., 17, 1855-1866.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
AHNAK nucleoprotein + H2O Homo sapiens AHNAK is lost in cells expressing active CAPN3. Conversely, AHNAK accumulates when calpain 3 is defective in skeletal muscle of calpainopathy patients ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
skeletal muscle calpain 3 activity promotes turnover of AHNAK in cell culture and in skeletal muscle Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
AHNAK nucleoprotein + H2O
-
 Homo sapiens ?
-
 ?
AHNAK nucleoprotein + H2O AHNAK is lost in cells expressing active CAPN3. Conversely, AHNAK accumulates when calpain 3 is defective in skeletal muscle of calpainopathy patients Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
CAPN3
-
 Homo sapiens