Inhibitors | Comment | Organism | Structure |
---|---|---|---|
benzyloxycarbonyl-LLY-fluoromethylketone | - |
Rattus norvegicus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | activates | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
58000 | - |
x * 58000, active form, SDS-PAGE | Rattus norvegicus |
80000 | - |
x * 80000, inactive form, SDS-PAGE | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
INS-1 832/13 cell | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-acetyl-LLY-7-amido-4-trifluoromethylcoumarin + H2O | - |
Rattus norvegicus | N-acetyl-LLY + 7-amino-4-trifluoromethylcoumarin | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 58000, active form, SDS-PAGE | Rattus norvegicus |
? | x * 80000, inactive form, SDS-PAGE | Rattus norvegicus |
Synonyms | Comment | Organism |
---|---|---|
m-calpain | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes | Rattus norvegicus |