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Literature summary for 3.4.22.52 extracted from

  • Villalpando Rodriguez, G.E.; Torriglia, A.
    Calpain 1 induce lysosomal permeabilization by cleavage of lysosomal associated membrane protein 2 (2013), Biochim. Biophys. Acta, 1833, 2244-2253.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
calpain VI inhibitor 78 nM used in assay conditions Mus musculus
calpain VI inhibitor 78 nM used in assay conditions Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosomal membrane
-
Mus musculus 5765
-
lysosomal membrane
-
Rattus norvegicus 5765
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
lysosomal associated membrane protein 2 + H2O Mus musculus calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 ?
-
?
lysosomal associated membrane protein 2 + H2O Rattus norvegicus calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MEF cell
-
Mus musculus
-
retina
-
Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
lysosomal associated membrane protein 2 + H2O calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 Mus musculus ?
-
?
lysosomal associated membrane protein 2 + H2O calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 Rattus norvegicus ?
-
?

Synonyms

Synonyms Comment Organism
calpain 1
-
Mus musculus
calpain 1
-
Rattus norvegicus

General Information

General Information Comment Organism
physiological function calpain is involved in lysosomal membrane permeabilization Mus musculus
physiological function calpain is involved in lysosomal membrane permeabilization Rattus norvegicus