Inhibitors | Comment | Organism | Structure |
---|---|---|---|
calpain VI inhibitor | 78 nM used in assay conditions | Mus musculus | |
calpain VI inhibitor | 78 nM used in assay conditions | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosomal membrane | - |
Mus musculus | 5765 | - |
lysosomal membrane | - |
Rattus norvegicus | 5765 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
lysosomal associated membrane protein 2 + H2O | Mus musculus | calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 | ? | - |
? | |
lysosomal associated membrane protein 2 + H2O | Rattus norvegicus | calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MEF cell | - |
Mus musculus | - |
retina | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
lysosomal associated membrane protein 2 + H2O | calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 | Mus musculus | ? | - |
? | |
lysosomal associated membrane protein 2 + H2O | calpain 1 is responsible for lysosomal permeabilization by cleavage of the lysosomal associated membrane protein 2 | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
calpain 1 | - |
Mus musculus |
calpain 1 | - |
Rattus norvegicus |
General Information | Comment | Organism |
---|---|---|
physiological function | calpain is involved in lysosomal membrane permeabilization | Mus musculus |
physiological function | calpain is involved in lysosomal membrane permeabilization | Rattus norvegicus |