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Literature summary for 3.4.22.52 extracted from

  • Shimazawa, M.; Suemori, S.; Inokuchi, Y.; Matsunaga, N.; Nakajima, Y.; Oka, T.; Yamamoto, T.; Hara, H.
    A novel calpain inhibitor, ((1S)-1-((((1S)-1-Benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945), reduces murine retinal cell death in vitro and in vivo (2010), J. Pharmacol. Exp. Ther., 332, 380-387.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester SNJ-1945 Mus musculus

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ Ca2+ requirement for half-maximal activation (0.003-0.05 mM) Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-spectrin + H2O Mus musculus
-
 ?
-
 ?
p35 + H2O Mus musculus
-
 p25 + ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
retina
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-spectrin + H2O
-
 Mus musculus ?
-
 ?
p35 + H2O
-
 Mus musculus p25 + ?
-
 ?

Synonyms

Synonyms Comment Organism
mu-calpain
-
 Mus musculus