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Literature summary for 3.4.22.52 extracted from

  • O’Connell, M.P.; Fiori, J.L.; Baugher, K.M.; Indig, F.E.; French, A.D.; Camilli, T.C.; Frank, B.P.; Earley, R.; Hoek, K.S.; Hasskamp, J.H.; Elias, E.G.; Taub, D.D.; Bernier, M.; Weeraratna, A.T.
    Wnt5A activates the calpain-mediated cleavage of filamin A (2009), J. Invest. Dermatol., 129, 1782-1789.
    View publication on PubMedView publication on EuropePMC

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
filamin A + H2O Homo sapiens
-
?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
G-361 cell
-
Homo sapiens
-
M93-047 cell
-
Homo sapiens
-
melanoma cell
-
Homo sapiens
-
primary cell
-
Homo sapiens
-
UACC-647 cell
-
Homo sapiens
-
UACC-903 cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
filamin A + H2O
-
Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
calpain 1
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens WNT5A knockdown decreases calpain 1 expression down
Homo sapiens Wnt5A activates calpain-1, leading to the cleavage of filamin A up