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Literature summary for 3.4.22.52 extracted from
- Role of mu-calpain in proteolytic cleavage of brain L-glutamic acid decarboxylase (2008), Brain Res., 1207C, 9-18.
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | mu-calpain is activated by neuronal stimulation and Ca2+-influx | Mus musculus |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| full-length glutamic acid decraboxylase67 + H2O | Mus musculus | in mu-calpain knockout mice, the level of truncated glutamic acid decarboxylase67 in the brain is greatly reduced compared with the wild-type. mu-Calpain is activated by neuronal stimulation and Ca2+-influx | truncated glutamic acid decarboxylase67 + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| full-length glutamic acid decraboxylase67 + H2O | - |
Mus musculus | truncated glutamic acid decarboxylase67 + ? | - |
? | |
| full-length glutamic acid decraboxylase67 + H2O | in mu-calpain knockout mice, the level of truncated glutamic acid decarboxylase67 in the brain is greatly reduced compared with the wild-type. mu-Calpain is activated by neuronal stimulation and Ca2+-influx | Mus musculus | truncated glutamic acid decarboxylase67 + ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| mu-calpain | - |
Mus musculus |
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Release 2023.1 (January 2023)
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