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Literature summary for 3.4.22.49 extracted from

  • Cipressa, F.; Morciano, P.; Bosso, G.; Mannini, L.; Galati, A.; Raffa, G.D.; Cacchione, S.; Musio, A.; Cenci, G.
    A role for Separase in telomere protection (2016), Nat. Commun., 7, 10405 .
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
additional information separase binds terminin proteins and HP1, and that it is enriched at telomeres Drosophila sp. (in: flies)
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Organism

Organism UniProt Comment Textmining
Drosophila sp. (in: flies)
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General Information

General Information Comment Organism
malfunction mutations in the Drosophila Separase encoding gene Sse lead not only to endoreduplication but also telomeric fusions, suggesting a role for Sse in telomere capping Drosophila sp. (in: flies)
physiological function Separase plays an evolutionarily conserved role in telomere protection Drosophila sp. (in: flies)