Literature summary for 3.4.22.49 extracted from

Ishiguro, T.; Tanaka, K.; Sakuno, T.; Watanabe, Y.
Shugoshin-PP2A counteracts casein-kinase-1-dependent cleavage of Rec8 by separase (2010), Nat. Cell Biol., 12, 500-506.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
Rec8 + H2O	Homo sapiens	the phosphorylations of Rec8 at S412 and the surrounding sites, which are most probably dependent on CK1, are essential for the cleavability of Rec8 by separase	fragments of Rec8	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Rec8 + H2O	the phosphorylations of Rec8 at S412 and the surrounding sites, which are most probably dependent on CK1, are essential for the cleavability of Rec8 by separase	Homo sapiens	fragments of Rec8	-	?

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Release 2023.1 (January 2023)