Localization | Comment | Organism | GeneOntology No. | Textmining |
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Organism | UniProt | Comment | Textmining |
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Arabidopsis thaliana | - |
ecotype Columbia | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cohesin + H2O | - |
Arabidopsis thaliana | fragments of cohesin | - |
? |
General Information | Comment | Organism |
---|---|---|
malfunction | Arabidopsis thaliana radially swollen 4 (rsw4), a temperature-sensitive mutant, harbors a mutation in At4g22970, the separase. Loss of separase function in rsw4 at the restrictive temperature is indicated by the widespread failure of replicated chromosomes to disjoin. rsw4 has neither pronounced cell cycle arrest nor anomalous spindle formation, rsw4 roots have disorganized cortical microtubules and accumulate the mitosis-specific cyclin, cyclin B1,1 | Arabidopsis thaliana |
physiological function | plant separase, in addition to cleaving cohesin, regulates cyclin B1,1, with profound ramifications for morphogenesis | Arabidopsis thaliana |