Protein Variants | Comment | Organism |
---|---|---|
additional information | Lpro regulates the activity of nuclear factor kappa B. Analysis of NF-kappa B-dependent reporter gene expression in BHK-21 cells (baby hamster kidney cells strain 21), demonstrate that infection with wild-type virus has an inhibitory effect compared to infection with a genetically engineered mutant (A12-LLV2) lacking the leader coding region | Foot-and-mouth disease virus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | Lpro is localized to the nucleus of infected cells, and there is a correlation between the translocation of Lpro and the decrease in the amount of nuclear p65/RelA, a subunit of NF-kappa B | Foot-and-mouth disease virus | 5634 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Foot-and-mouth disease virus | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
Lbpro | - |
Foot-and-mouth disease virus |
Leader proteinase | - |
Foot-and-mouth disease virus |