Literature summary for 3.4.22.44 extracted from

Shin, B.; Oh, H.; Park, S.M.; Han, H.E.; Ye, M.; Song, W.K.; Park, W.J.
Intracellular cleavage of amyloid beta by a viral protease NIa prevents amyloid beta-mediated cytotoxicity (2014), PLoS ONE, 9, e98650.

Search for more literature for 3.4.22.44

Cloned(Commentary)

Cloned (Comment)	Organism
-	turnip mosaic virus

Organism

Organism	UniProt	Comment	Textmining
turnip mosaic virus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	turnip mosaic virus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
amyloid beta + H2O	the enzyme cleaves monomeric and oligomeric amyloid beta at a similar rate in vitro	turnip mosaic virus	?	-	?

Synonyms

Synonyms	Comment	Organism
NIA	-	turnip mosaic virus

General Information

General Information	Comment	Organism
physiological function	oligomeric amyloid beta-induced cytotoxicity and mitochondrial dysfunction are significantly ameliorated by the enzyme. The enzyme prevents mitochondrial deposition of amyloid beta	turnip mosaic virus

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Release 2023.1 (January 2023)