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Literature summary for 3.4.22.43 extracted from

  • Funkelstein, L.; Lu, W.D.; Koch, B.; Mosier, C.; Toneff, T.; Taupenot, L.; O'Connor, D.T.; Reinheckel, T.; Peters, C.; Hook, V.
    Human cathepsin V protease participates in production of enkephalin and NPY neuropeptide neurotransmitters (2012), J. Biol. Chem., 287, 15232-15241.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
secretory vesicle
-
Homo sapiens 99503
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
x * 24000, mature enzyme, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
neuropeptide Y + H2O Homo sapiens
-
?
-
?
proenkephalin + H2O Homo sapiens
-
(Met)enkephalin + ?
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens O60911
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain cortex
-
Homo sapiens
-
hippocampus
-
Homo sapiens
-
PC-12 cell
-
Homo sapiens
-
SK-N-MC cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Boc-Gly-Lys-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens Boc-Gly-Lys-Arg + 7-amino-4-methylcoumarin
-
?
neuropeptide Y + H2O
-
Homo sapiens ?
-
?
proenkephalin + H2O
-
Homo sapiens (Met)enkephalin + ?
-
?
Z-Arg-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens Z-Arg-Arg + 7-amino-4-methylcoumarin
-
?
Z-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens Z-Phe-Arg + 7-amino-4-methylcoumarin
-
?

Subunits

Subunits Comment Organism
? x * 24000, mature enzyme, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
cathepsin V
-
Homo sapiens
CTSV also known as CTSL2 Homo sapiens

General Information

General Information Comment Organism
metabolism cathepsin V participates in the production of enkephalin and neuropeptide Y neurotransmitters in secretory vesicles Homo sapiens