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Literature summary for 3.4.22.43 extracted from

  • Piovan, L.; Alves, M.F.; Juliano, L.; Broemme, D.; Cunha, R.L.; Andrade, L.H.
    Structure-activity relationships of hypervalent organochalcogenanes as inhibitors of cysteine cathepsins V and S (2011), Bioorg. Med. Chem., 19, 2009-2014.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
(1R)-1-{2-[butyl(dichloro)-l4-tellanyl]phenyl}ethyl methyl ether less than 10% residual activity at 0.001 mM Homo sapiens
(1R)-1-{2-[dibromo(butyl)-l4-tellanyl]phenyl}ethyl methyl ether less than 10% residual activity at 0.001 mM Homo sapiens
(1S)-1-{2-[butyl(dichloro)-l4-tellanyl]phenyl}ethyl methyl ether less than 10% residual activity at 0.001 mM Homo sapiens
(1S)-1-{2-[dibromo(butyl)-l4-tellanyl]phenyl}ethyl methyl ether less than 10% residual activity at 0.001 mM Homo sapiens
2-[butyl(dichloro)-l4-tellanyl]benzyl methyl ether about 10% residual activity at 0.001 mM Homo sapiens
2-[dibromo(butyl)-l4-tellanyl]benzyl methyl ether less than 10% residual activity at 0.001 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Cbz-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens Cbz-Phe-Arg + 7-amino-4-methylcoumarin
-
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