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BRENDA support

Literature summary for 3.4.22.43 extracted from

  • Renko, M.; Sabotic, J.; Mihelic, M.; Brzin, J.; Kos, J.; Turk, D.
    Versatile loops in mycocypins inhibit three protease families (2010), J. Biol. Chem., 285, 308-316.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Pichia pastoris Homo sapiens

Crystallization (Commentary)

Crystallization (Comment) Organism
cathepsin V in complex with clitocypin, vapor diffusion method, using 0.4 M Li2SO4, 12% (w/v) polyethylene glycol 800, 20% (v/v) glycerol Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
clitocypin
-
Homo sapiens
macrocypin-1
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens O60911
-
-

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00000008
-
clitocypin pH and temperature not specified in the publication Homo sapiens
0.00000069
-
macrocypin-1 pH and temperature not specified in the publication Homo sapiens