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Literature summary for 3.4.22.43 extracted from

  • Cheng, T.; Tjabringa, G.S.; van Vlijmen-Willems, I.M.; Hitomi, K.; van Erp, P.E.; Schalkwijk, J.; Zeeuwen, P.L.
    The cystatin M/E-controlled pathway of skin barrier formation: expression of its key components in psoriasis and atopic dermatitis (2009), Br. J. Dermatol., 161, 253-264.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
cystatin M/E the antiprotease activity of cystatin M/E inhibits the activity of cathepsin V Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
Homo sapiens
-
bronchus
-
Homo sapiens
-
epiglottis
-
Homo sapiens
-
esophagus
-
Homo sapiens
-
foot sole
-
Homo sapiens
-
gingiva
-
Homo sapiens
-
heart
-
Homo sapiens
-
ileum
-
Homo sapiens
-
kidney
-
Homo sapiens
-
liver
-
Homo sapiens
-
lymph node
-
Homo sapiens
-
additional information no expression in colon, lung, trachea, ureter, testis, heart, muscle, aorta, spleen, and mammary gland Homo sapiens
-
pancreas
-
Homo sapiens
-
pharynx
-
Homo sapiens
-
skin
-
Homo sapiens
-
stomach
-
Homo sapiens
-
tongue
-
Homo sapiens
-
vocal fold
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
cathepsin L2/V
-
Homo sapiens
CTSV
-
Homo sapiens

Expression

Organism Comment Expression
Homo sapiens there is decreased expression of cathepsin V in lesional atopic dermatitis and psoriasis epidermis at the mRNA level as well as the protein level down