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Literature summary for 3.4.22.43 extracted from

  • Hagemann, S.; Guenther, T.; Dennemaerker, J.; Lohmueller, T.; Broemme, D.; Schuele, R.; Peters, C.; Reinheckel, T.
    The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles (2004), Eur. J. Cell Biol., 83, 775-780.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
transgenic expression in cathepsin L-deficient mice, phylogenetic tree Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information the enzyme can complement cathepsin L-deficient mice by expression of cathepsin V in epidermis and hair follicles, the mutant mice suffer from a complex skin phenotype consisting of hair loss and epidermal hyperplasia with hyperproliferation of basal epidermal keratinocytes, acanthosis, and hyperkeratosis, overview Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cornea
-
Homo sapiens
-
epidermis
-
Homo sapiens
-
additional information selective, tissue-specific expression Homo sapiens
-
testis
-
Homo sapiens
-
thymus
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
cathepsin L2
-
Homo sapiens