Cloned (Comment) | Organism |
---|---|
expression in Pichia pastoris | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-morpholincarbonyl-Leu-homophenylalaninevinyl sulfone-phenyl | - |
Homo sapiens | |
calpeptin | - |
Homo sapiens | |
chymostatin | - |
Homo sapiens | |
cystatin | - |
Homo sapiens | |
iodoacetic acid | - |
Homo sapiens | |
leupeptin | - |
Homo sapiens | |
trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane | i.e. E-64 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
intracellular | the corneal enzyme stays within cells and is not secreted | Homo sapiens | 5622 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37330 | - |
preproprotein, containing a 17 amino acid signal peptide, a 96 amino acid propeptide and a 221 amino acid mature region, calculation from sequence of cDNA | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | O60911 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | recombinant enzyme is partially and heterogenously glycosylated | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
testis | - |
Homo sapiens | - |
thymus | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
N-benzyloxycarbonyl-L-Phe-L-Arg-4-methylcoumarin 7-amide + H2O | - |
Homo sapiens | N-benzyloxycarbonyl-L-Phe-L-Arg + 7-amino-4-methylcoumarin | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.7 | - |
- |
Homo sapiens |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
4 | 7.2 | less than 50% of maximal activity above and below | Homo sapiens |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
2 h stable | Homo sapiens |
6.5 | - |
2 h, residual acitviy | Homo sapiens |
7 | - |
1 h, residual acitviy | Homo sapiens |