Literature summary for 3.4.22.40 extracted from

Adachi, H.; Tsujimoto, M.; Fukasawa, M.; Sato, Y.; Arai, H.; Inoue, K.; Nishimura, T.
cDNA cloning and expression of chicken aminopeptidase H, possessing endopeptidase as well as aminopeptidase activity (1997), Eur. J. Biochem., 245, 283-288.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in COS7 cells	Gallus gallus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
intracellular	-	Gallus gallus	5622	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
52000	-	8 * 52000, SDS-PAGE	Gallus gallus
400000	-	gel filtration	Gallus gallus

Organism

Organism	UniProt	Comment	Textmining
Gallus gallus	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
Inactivates bleomycin B2 (a cytotoxic glycometallopeptide) by hydrolysis of a carboxyamide bond of beta-aminoalanine, but also shows general aminopeptidase activity. The specificity varies somewhat with source, but amino acid arylamides of Met, Leu and Ala are preferred	endopeptidase and aminopeptidase activity	Gallus gallus	a

Source Tissue

Source Tissue	Comment	Organism	Textmining
muscle	-	Gallus gallus	-

Subunits

Subunits	Comment	Organism
octamer	8 * 52000, SDS-PAGE	Gallus gallus

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Release 2023.1 (January 2023)