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Literature summary for 3.4.22.38 extracted from

  • Borel, O.; Gineyts, E.; Bertholon, C.; Garnero, P.
    Cathepsin K preferentially solubilizes matured bone matrix (2012), Calcif. Tissue Int., 91, 32-39.
    View publication on PubMed
Search for more literature for 3.4.22.38

Inhibitors

Inhibitors Comment Organism Structure
SB-357114 specific inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-isomerized C-telopeptide + H2O Homo sapiens
-
 ?
-
 ?
beta-isomerized C-telopeptide + H2O Homo sapiens
-
 ?
-
 ?
Collagen type I + H2O Homo sapiens
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-isomerized C-telopeptide + H2O
-
 Homo sapiens ?
-
 ?
beta-isomerized C-telopeptide + H2O
-
 Homo sapiens ?
-
 ?
Collagen type I + H2O
-
 Homo sapiens ?
-
 ?

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.00000016
-
 SB-357114 in 100 mM sodium acetate buffer (pH 5.5), at 37°C Homo sapiens

General Information

General Information Comment Organism
physiological function cathepsin K preferentially solubilizes matured bone matrix Homo sapiens