Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Homo sapiens | 5764 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
collagen I + H2O | Homo sapiens | - |
? | - |
? | |
Collagen IV + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
dermis | in the dermis, cathepsin K is expressed only under certain circumstances such as scarring or inflammation | Homo sapiens | - |
skin fibroblast | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
collagen I + H2O | - |
Homo sapiens | ? | - |
? | |
Collagen IV + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
catK | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | ligand of receptor activator of nuclear factor-kappaB does not induce cathepsin K expression in fibroblasts | additional information |
Homo sapiens | in fibroblasts, interleukin-1alpha and cellular confluence upregulate cathepsin K expression | up |
General Information | Comment | Organism |
---|---|---|
physiological function | cathepsin K plays a role in intracellular collagen degradation after endocytosis | Homo sapiens |