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BRENDA support

Literature summary for 3.4.22.38 extracted from

  • Fuller, K.; Lindstrom, E.; Edlund, M.; Henderson, I.; Grabowska, U.; Szewczyk, K.A.; Moss, R.; Samuelsson, B.; Chambers, T.J.
    The resorptive apparatus of osteoclasts supports lysosomotropism and increases potency of basic versus non-basic inhibitors of cathepsin K (2010), Bone, 46, 1400-1407.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
MV061606
-
Homo sapiens
MV076159
-
Homo sapiens
odanacatib
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
osteoclast
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
catK
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000023
-
pH and temperature not specified in the publication Homo sapiens MV061606
0.000034
-
pH and temperature not specified in the publication Homo sapiens odanacatib