Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.38 extracted from

  • Vinardell, T.; Dejica, V.; Poole, A.R.; Mort, J.S.; Richard, H.; Laverty, S.
    Evidence to suggest that cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis (2009), Osteoarthritis Cartilage, 17, 375-383.
    View publication on PubMed
Search for more literature for 3.4.22.38

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
collagen II + H2O Equus caballus cathepsin K is a cysteine protease which can also cleave the triple helix of type II collagen ?
-
 ?
additional information Equus caballus cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis, it plays a role in both lesional and peri-lesional regions, overview ?
-
 ?
additional information Equus caballus cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis ?
-
 ?
type II collagen + H2O Equus caballus cathepsin K cleaves the triple helix of type II collagen ?
-
 ?

Organism

Organism UniProt Comment Textmining
Equus caballus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
articular cartilage
-
 Equus caballus
-
cartilage articluar, from the metacarpophalangeal and healthy joints, immunohistochemic identification in different regions of the tissue from healthy and osteoarthritic animals, overview Equus caballus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
collagen II + H2O
-
 Equus caballus ?
-
 ?
collagen II + H2O cathepsin K is a cysteine protease which can also cleave the triple helix of type II collagen Equus caballus ?
-
 ?
additional information cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis, it plays a role in both lesional and peri-lesional regions, overview Equus caballus ?
-
 ?
additional information cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis Equus caballus ?
-
 ?
type II collagen + H2O cathepsin K cleaves the triple helix of type II collagen Equus caballus ?
-
 ?