Application | Comment | Organism |
---|---|---|
pharmacology | CTSK is a possible therapeutic target in the treatment of obesity | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
E64 | blocks adipocyte differentiation in early stages | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
lysosome | - |
Mus musculus | 5764 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
collagen I + H2O | Mus musculus | cathepsin K regulates adipocyte differentiation, possible involvement of type I collagen degradation and regulation of collagen type I expression, molecular mechanism, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
3T3-L1 cell | ATCC CL-173 | Mus musculus | - |
adipocyte | CTSK is active mainly in the early stages of adipogenesis | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
collagen I + H2O | cathepsin K regulates adipocyte differentiation, possible involvement of type I collagen degradation and regulation of collagen type I expression, molecular mechanism, overview | Mus musculus | ? | - |
? | |
collagen I + H2O | type I collagen degradation | Mus musculus | ? | - |
? | |
Gelatin + H2O | substrate for CTSK zymography | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CTSK | - |
Mus musculus |