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Literature summary for 3.4.22.37 extracted from

  • Kuboniwa, M.; Amano, A.; Hashino, E.; Yamamoto, Y.; Inaba, H.; Hamada, N.; Nakayama, K.; Tribble, G.D.; Lamont, R.J.; Shizukuishi, S.
    Distinct roles of long/short fimbriae and gingipains in homotypic biofilm development by Porphyromonas gingivalis (2009), BMC Microbiol., 9, 105.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Porphyromonas gingivalis
-
-
-

Synonyms

Synonyms Comment Organism
Arg-gingipain A
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Porphyromonas gingivalis
Arg-gingipain B
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Porphyromonas gingivalis
RgpA
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Porphyromonas gingivalis
RgpB
-
Porphyromonas gingivalis

General Information

General Information Comment Organism
malfunction the roles of several virulence factors in homotypic biofilm development by Porphyromonas gingivalis. A RgpA/B double mutant develops channel-like biofilms with fibrillar and tall microcolonies in PBS. When this mutant is studied in diluted trypticase soy broth, there is an increase in the number of peaks and the morphology changed to taller and loosely packed biofilms. Results suggests that Rgp controlls microcolony morphology and biovolume and acts coordinately with other virulence factors such as long (FimA) and short (Mfa) fimbriae to regulate the development of mature biofilms Porphyromonas gingivalis