Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.37 extracted from

  • Kato, T.; Tsuda, T.; Inaba, H.; Kawai, S.; Okahashi, N.; Shibata, Y.; Abiko, Y.; Amano, A.
    Porphyromonas gingivalis gingipains cause G(1) arrest in osteoblastic/stromal cells (2008), Oral Microbiol. Immunol., 23, 158-164.
    View publication on PubMed
Search for more literature for 3.4.22.37

Cloned(Commentary)

Cloned (Comment) Organism
expression of wild-type and mutant enzymes in murine ST2 osteoblastic/stromal cells Porphyromonas gingivalis

Protein Variants

Protein Variants Comment Organism
additional information construction of enzyme-deficient mutants KDP136 with DELTArgpADELTArgpBDELTAkgp, and KDP133 with DELTAkgp. The mutants do not, in contrast to the wild-type enzyme, inhibit cellular proliferation and don not arrest the cell cycle in the G0/G1 phase as well as decrease the expression levels of the cell-cycle regulatory molecules cyclin D and cyclin E in murine ST2 cells, overview Porphyromonas gingivalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Porphyromonas gingivalis gingipains reduce cyclin expression and cause early G1 arrest, leading to the inhibition of cellular proliferation in murine ST2 osteoblastic/stromal cells, overview ?
-
 ?
additional information Porphyromonas gingivalis ATCC 33277 gingipains reduce cyclin expression and cause early G1 arrest, leading to the inhibition of cellular proliferation in murine ST2 osteoblastic/stromal cells, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Porphyromonas gingivalis
-
 strain ATCC33277
-
Porphyromonas gingivalis ATCC 33277
-
 strain ATCC33277
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information gingipains reduce cyclin expression and cause early G1 arrest, leading to the inhibition of cellular proliferation in murine ST2 osteoblastic/stromal cells, overview Porphyromonas gingivalis ?
-
 ?
additional information gingipains reduce cyclin expression and cause early G1 arrest, leading to the inhibition of cellular proliferation in murine ST2 osteoblastic/stromal cells, overview Porphyromonas gingivalis ATCC 33277 ?
-
 ?

Synonyms

Synonyms Comment Organism
gingipain R
-
 Porphyromonas gingivalis
RgpA
-
 Porphyromonas gingivalis
RgpB
-
 Porphyromonas gingivalis