Protein Variants | Comment | Organism |
---|---|---|
additional information | Rgp null mutant strain KDP133 shows platelet aggregation similar to the wild-type strain ATCC 33277, while neither the Rgp/Kgp null mutant strain, nor the adhesin null mutant strain show platelet aggregation | Porphyromonas gingivalis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
RgpA-HagA polyprotein + H2O | Porphyromonas gingivalis | processing of the precursor by Rgp | ? | - |
? | |
RgpA-Hgp polyprotein + H2O | Porphyromonas gingivalis | processing of the precursor by Rgp, Porphyromonas gingivalis-induced platelet aggregation in platelet-rich plasma depends on processed Hgp44 adhesin but not directly on Rgp proteinase, the adhesin is also processed by Lys-gingipain Kgp, EC 3.4.22.47 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Porphyromonas gingivalis | - |
wild-type strain ATCC 33277 | - |
Source Tissue | Comment | Organism | Textmining |
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Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
RgpA-HagA polyprotein + H2O | processing of the precursor by Rgp | Porphyromonas gingivalis | ? | - |
? | |
RgpA-Hgp polyprotein + H2O | processing of the precursor by Rgp | Porphyromonas gingivalis | ? | - |
? | |
RgpA-Hgp polyprotein + H2O | processing of the precursor by Rgp, Porphyromonas gingivalis-induced platelet aggregation in platelet-rich plasma depends on processed Hgp44 adhesin but not directly on Rgp proteinase, the adhesin is also processed by Lys-gingipain Kgp, EC 3.4.22.47 | Porphyromonas gingivalis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | RgpA can occur as monomer or as heterodimer fused to adhesins and a hemagglutinin domain, while RgpB possesses only a small hemagglutinin domain, domain structure, overview | Porphyromonas gingivalis |
Synonyms | Comment | Organism |
---|---|---|
Rgp proteinase | - |
Porphyromonas gingivalis |