Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.37 extracted from

  • Naito, M.; Sakai, E.; Shi, Y.; Ideguchi, H.; Shoji, M.; Ohara, N.; Yamamoto, K.; Nakayama, K.
    Porphyromonas gingivalis-induced platelet aggregation in plasma depends on Hgp44 adhesin but not Rgp proteinase (2006), Mol. Microbiol., 59, 152-167.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information Rgp null mutant strain KDP133 shows platelet aggregation similar to the wild-type strain ATCC 33277, while neither the Rgp/Kgp null mutant strain, nor the adhesin null mutant strain show platelet aggregation Porphyromonas gingivalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
RgpA-HagA polyprotein + H2O Porphyromonas gingivalis processing of the precursor by Rgp ?
-
?
RgpA-Hgp polyprotein + H2O Porphyromonas gingivalis processing of the precursor by Rgp, Porphyromonas gingivalis-induced platelet aggregation in platelet-rich plasma depends on processed Hgp44 adhesin but not directly on Rgp proteinase, the adhesin is also processed by Lys-gingipain Kgp, EC 3.4.22.47 ?
-
?

Organism

Organism UniProt Comment Textmining
Porphyromonas gingivalis
-
wild-type strain ATCC 33277
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
RgpA-HagA polyprotein + H2O processing of the precursor by Rgp Porphyromonas gingivalis ?
-
?
RgpA-Hgp polyprotein + H2O processing of the precursor by Rgp Porphyromonas gingivalis ?
-
?
RgpA-Hgp polyprotein + H2O processing of the precursor by Rgp, Porphyromonas gingivalis-induced platelet aggregation in platelet-rich plasma depends on processed Hgp44 adhesin but not directly on Rgp proteinase, the adhesin is also processed by Lys-gingipain Kgp, EC 3.4.22.47 Porphyromonas gingivalis ?
-
?

Subunits

Subunits Comment Organism
More RgpA can occur as monomer or as heterodimer fused to adhesins and a hemagglutinin domain, while RgpB possesses only a small hemagglutinin domain, domain structure, overview Porphyromonas gingivalis

Synonyms

Synonyms Comment Organism
Rgp proteinase
-
Porphyromonas gingivalis