Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the enzyme and apoptosis in SF-21 cell line are induced by the conditioned medium of the entomopathogenic fungus, Nomuraea rileyi, cell phenotype, overview | Spodoptera frugiperda |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
carbobenzyloxy-Asp-Glu-Val-Asp-fluoromethyl ketone | specific to suppress the activity of Sf-caspase-1 by blocking amplification of Sfcaspase-1 | Spodoptera frugiperda | |
carbobenzyloxy-Val-Ala-Asp-fluoromethyl ketone | a broad-spectrum inhibitor of initiator caspase | Spodoptera frugiperda |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Spodoptera frugiperda | caspase-1 is involved in this apoptosis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Spodoptera frugiperda | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | pro-Sf-caspase-1 with a short domain is activated by an apical caspase through proteolytic cleavage, at the caspase-recognition site between the large and small subunits of pro-Sfcaspase-1, when apoptotic signaling is triggered | Spodoptera frugiperda |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
SF-21 cell | - |
Spodoptera frugiperda | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | caspase-1 is involved in this apoptosis | Spodoptera frugiperda | ? | - |
? |