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Literature summary for 3.4.22.36 extracted from
- Involvement of caspase 1 and its activator Ipaf upstream of mitochondrial events in apoptosis (2006), FEBS J., 273, 2766-2778.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| protease-activating factor | activates caspase 1 in p53-dependent apoptosis | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | caspase 1 activated by protease-activating factor acts upstream of mitochondria to cause release of proteins that are known to mediate apoptosis | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| MCF-7 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | caspase 1 activated by protease-activating factor acts upstream of mitochondria to cause release of proteins that are known to mediate apoptosis | Homo sapiens | ? | - |
? | |
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