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Literature summary for 3.4.22.36 extracted from

  • Thornberry, N.A.; Rano, T.A.; Peterson, E.P.; et al.
    A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis (1997), J. Biol. Chem., 272, 17907-17911.
    View publication on PubMed
Search for more literature for 3.4.22.36

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
interferon-gamma inducing factor + H2O Homo sapiens cleavage site: LESD-/- ?
-
 ?
pro-interleukin-1beta + H2O Homo sapiens pro-interleukin-1beta cleavage site 1 is FEAD-/-, pro-interleukin-1beta cleavage site II is YVHD-/- 17000 Da fragment + 28000 Da fragment
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification the activation site in caspase is WFKD (P4,P3,P2,P1) Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
interferon-gamma inducing factor + H2O cleavage site: LESD-/- Homo sapiens ?
-
 ?
pro-interleukin-1beta + H2O pro-interleukin-1beta cleavage site 1 is FEAD-/-, pro-interleukin-1beta cleavage site II is YVHD-/- Homo sapiens 17000 Da fragment + 28000 Da fragment
-
 ?