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Literature summary for 3.4.22.35 extracted from

  • Lee, Y.A.; Nam, Y.H.; Min, A.; Kim, K.A.; Nozaki, T.; Saito-Nakano, Y.; Mirelman, D.; Shin, M.H.
    Entamoeba histolytica-secreted cysteine proteases induce IL-8 production in human mast cells via a PAR2-independent mechanism (2014), Parasite, 21, 1-1.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Entamoeba histolytica
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
trophozoite
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 Entamoeba histolytica
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Z-Arg-Arg-4-nitroanilide + H2O
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 Entamoeba histolytica Z-Arg-Arg + 4-nitroaniline
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 ?

General Information

General Information Comment Organism
physiological function Entamoeba histolytica-secreted cysteine proteases induce interleukin-8 production in human mast cells via a protease-activated receptor 2-independent mechanism which contributes to interleukin-8-mediated tissue inflammatory responses during the early phase of human amoebiasis Entamoeba histolytica