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Literature summary for 3.4.22.34 extracted from

  • Teng, L.; Wada, H.; Zhang, S.
    Identification and functional characterization of legumain in amphioxus Branchiostoma belcheri (2010), Biosci. Rep., 30, 177-186.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
recombinantly expressed in yeast Branchiostoma belcheri

Inhibitors

Inhibitors Comment Organism Structure
cystatin from egg-white Branchiostoma belcheri
iodoacetamide
-
Branchiostoma belcheri
N-ethylmaleimide
-
Branchiostoma belcheri

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
active protein Branchiostoma belcheri

Organism

Organism UniProt Comment Textmining
Branchiostoma belcheri
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein putative Asn-glycosylation sites at Asn85 and Asn270 Branchiostoma belcheri
proteolytic modification Both recombinant legumain expressed in yeast and endogenous legumain are able to be converted into active protein of approximately 37 kDa via a C-terminal autocleavage at acid pH values Branchiostoma belcheri

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Cbz-Ala-Ala-Asn-7-amido-4-methylcoumarin + H2O
-
Branchiostoma belcheri Cbz-Ala-Ala-Asn + 7-amino-4-methylcoumarin
-
?

Synonyms

Synonyms Comment Organism
legumain
-
Branchiostoma belcheri

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
Branchiostoma belcheri