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Literature summary for 3.4.22.30 extracted from

  • Khan, A.; Connerton, I.F.; Cummings, N.J.; Hussain, S.; Noble, M.A.; Taylor, M.A.J.; Thomas, E.W.; Verma, C.; Brocklehurst, K.
    The kinetically influential ionizations of caricain D158N revealed by using 4,4'-dipyrimidyl disulfide as a reactivity probe (1998), Biochem. Soc. Trans., 26, S172.
    View publication on PubMed
Search for more literature for 3.4.22.30

Protein Variants

Protein Variants Comment Organism
D158N altered ionization kinetics required for catalysis Carica papaya

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information kinetics of wild-type and D158N mutant Carica papaya

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
protein + H2O Carica papaya
-
 peptides
-
 ?

Organism

Organism UniProt Comment Textmining
Carica papaya
-
-
-

Reaction

Reaction Comment Organism Reaction ID
hydrolysis of proteins with broad specificity for peptide bonds, similar to those of papain and chymopapain residue E50 is part of the electrostatic switch required for catalytic activity, mechanism, possible role of D158 Carica papaya
a

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
protein + H2O
-
 Carica papaya peptides
-
 ?

Synonyms

Synonyms Comment Organism
Papaya proteinase OMEGA
-
 Carica papaya