Literature summary for 3.4.22.29 extracted from

Maghsoudi, N.; Tafreshi, N.K.h.; Khodagholi, F.; Zakeri, Z.; Esfandiarei, M.; Hadi-Alijanvand, H.; Sabbaghian, M.; Maghsoudi, A.H.; Sajadi, M.; Zohri, M.; Moosavi, M.; Zeinoddini, M.
Targeting enteroviral 2A protease by a 16-mer synthetic peptide: inhibition of 2Apro-induced apoptosis in a stable Tet-on HeLa cell line (2010), Virology, 399, 39-45.

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Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3)pLysS	Coxsackievirus B3

Inhibitors

Inhibitors	Comment	Organism	Structure
Gly-Arg-Thr-Thr-Leu-Ser-Thr-Arg-Gly-Pro-Pro-Arg-Gly-Gly-Pro-Gly	-	Coxsackievirus B3

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
eIF4G + H2O	Coxsackievirus B3	eukaryotic initiation factor-4G	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Coxsackievirus B3	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
ion-exchange chromatography (Q-Sepharose)	Coxsackievirus B3

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
eIF4G + H2O	eukaryotic initiation factor-4G	Coxsackievirus B3	?	-	?

Synonyms

Synonyms	Comment	Organism
2A protease	-	Coxsackievirus B3
2Apro	-	Coxsackievirus B3

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Release 2023.1 (January 2023)