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Literature summary for 3.4.22.29 extracted from

  • Wang, Q.M.; Johnson, R.B.; Sommergruber, W.; Shepherd, T.A.
    Development of in vitro peptide substrates for human rhinovirus-14 2A protease (1998), Arch. Biochem. Biophys., 356, 12-18.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
Aprotinin 0.015 mM, 23% inhibition Human rhinovirus sp.
Elastinal 0.1 mM, 68% inhibition Human rhinovirus sp.
iodoacetamide 1 mM, complete inhibition Human rhinovirus sp.
LY343813 0.025 mM, 61% inhibition Human rhinovirus sp.
LY343814 0.025 mM, 59% inhibition Human rhinovirus sp.
LY353350 0.025 mM, 67% inhibition Human rhinovirus sp.
additional information no inhibition by pepstatin Human rhinovirus sp.
NEM 1 mM, complete inhibition Human rhinovirus sp.
tosyl-L-leucine-chloromethyl ketone 1 mM, complete inhibition Human rhinovirus sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
16000
-
x * 16000, SDS-PAGE Human rhinovirus sp.

Organism

Organism UniProt Comment Textmining
Human rhinovirus sp.
-
serotypes 14
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Human rhinovirus sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DIKSYGLGPRYGG + H2O
-
Human rhinovirus sp. DIKSY + GLGPRYGG
-
?
GRTTLST-(3-nitrotyrosine)-GPPR-(lysine anthranilide)-Y + H2O
-
Human rhinovirus sp. GRTTLST-(3-nitrotyrosine) + GPPR-(lysine anthranilide)-Y
-
?
RKGDIKS-(3-nitrotyrosine)-GPGP-(lysine-anthranilide)-Y + H2O
-
Human rhinovirus sp. RKGDIKS-(3-nitrotyrosine) + GPGP-(lysine-anthranilide)-Y
-
?
RKGDIKSY-p-nitroanilide + H2O
-
Human rhinovirus sp. RKGDIKSY + p-nitroaniline
-
?
RKGDIKSYG + H2O
-
Human rhinovirus sp. RKGDIKSY + glycine
-
?
RKGDIKSYGLGPR + H2O
-
Human rhinovirus sp. RKGDIKSY + GLGPR
-
?
RKGDIKSYGLGPRYGG + H2O
-
Human rhinovirus sp. RKGDIKSY + GLGPRYGG
-
?
RKGDIKT-(3-nitrotyrosine)-GPGP-(lysine-anthranilide)-Y + H2O
-
Human rhinovirus sp. RKGDIKT-(3-nitrotyrosine) + GPGP-(lysine-anthranilide)-Y
-
?
TRPIITT-(3-nitrotyrosine)-GPSD-(lysine-anthranilate)-Y + H2O
-
Human rhinovirus sp. TRPIITT-(3-nitrotyrosine) + GPSD-(lysine-anthranilate)-Y
-
?

Subunits

Subunits Comment Organism
? x * 16000, SDS-PAGE Human rhinovirus sp.