Cloned (Comment) | Organism |
---|---|
- |
Enterovirus C |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | in trans cleavage activity | Enterovirus C | |
1,10-phenanthroline | - |
Human rhinovirus sp. | |
EDTA | not | Enterovirus C | |
additional information | - |
coxsackievirus | |
additional information | - |
enterovirus | |
additional information | no inhibition by 1,7-phenanthroline and DTT; no inhibition by EGTA | Enterovirus C | |
additional information | - |
Human rhinovirus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
poliovirus polypeptide + H2O | Enterovirus C | involved in primary processing of poliovirus | ? | - |
? | |
poliovirus polypeptide + H2O | enterovirus | involved in primary processing of poliovirus | ? | - |
? | |
poliovirus polypeptide + H2O | coxsackievirus | involved in primary processing of poliovirus | ? | - |
? | |
poliovirus polypeptide + H2O | Human rhinovirus sp. | involved in primary processing of poliovirus | ? | - |
? | |
poliovirus polypeptide + H2O | Enterovirus C | together with 3C protease | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
coxsackievirus | - |
B4 | - |
coxsackievirus | - |
types B1, A9, A21 | - |
enterovirus | - |
bovine enterovirus | - |
enterovirus | - |
bovine enterovirus type 70 | - |
Enterovirus C | - |
type 1 (Mahoney strain) | - |
Human rhinovirus sp. | - |
serotypes 2 | - |
Human rhinovirus sp. | - |
serotypes 14 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1C'D2A precursor polypeptide + H2O | i.e. autocatalytic cis cleavage activity, cleaves at 1D/2A junction in very rapid cotranslational reaction | Enterovirus C | ? | - |
? | |
capsid precursor protein P1 + H2O | - |
Enterovirus C | viral protein 1ABC + viral protein 1D | - |
? | |
additional information | - |
enterovirus | ? | - |
? | |
additional information | - |
coxsackievirus | ? | - |
? | |
additional information | - |
Human rhinovirus sp. | ? | - |
? | |
additional information | no cleavage by single-site mutant enzymes with substitutions at Cys55, Cys57, Cys115 or His117 | Enterovirus C | ? | - |
? | |
P1/P2 precursor polypeptide + H2O | from poliovirus | Enterovirus C | poliovirus 1C'D polypeptide + proteinase 2Apro | - |
? | |
P1/P2 precursor polypeptide + H2O | from poliovirus | Human rhinovirus sp. | poliovirus 1C'D polypeptide + proteinase 2Apro | - |
? | |
picornavirus polyprotein + H2O | - |
Enterovirus C | hydrolyzed picornavirus polyprotein | - |
? | |
picornavirus polyprotein + H2O | - |
enterovirus | hydrolyzed picornavirus polyprotein | - |
? | |
picornavirus polyprotein + H2O | - |
coxsackievirus | hydrolyzed picornavirus polyprotein | - |
? | |
picornavirus polyprotein + H2O | - |
Human rhinovirus sp. | hydrolyzed picornavirus polyprotein | - |
? | |
poliovirus polypeptide + H2O | involved in primary processing of poliovirus | Enterovirus C | ? | - |
? | |
poliovirus polypeptide + H2O | involved in primary processing of poliovirus | enterovirus | ? | - |
? | |
poliovirus polypeptide + H2O | involved in primary processing of poliovirus | coxsackievirus | ? | - |
? | |
poliovirus polypeptide + H2O | involved in primary processing of poliovirus | Human rhinovirus sp. | ? | - |
? | |
poliovirus polypeptide + H2O | together with 3C protease | Enterovirus C | ? | - |
? |