Literature summary for 3.4.22.27 extracted from

Tully, D.C.; Liu, H.; Chatterjee, A.K.; Alper, P.B.; Williams, J.A.; Roberts, M.J.; Mutnick, D.; Woodmansee, D.H.; Hollenbeck, T.; Gordon, P.; Chang, J.; Tuntland, T.; Tumanut, C.; Li, J.; Harris, J.L.; Karanewsky, D.S.
Arylaminoethyl carbamates as a novel series of potent and selective cathepsin S inhibitors (2006), Bioorg. Med. Chem. Lett., 16, 5107-5111.

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Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	synthesis and inhibitory effects of diverse arylaminoethyl carbamate inhibitors possessing a substrate peptidomimetic scaffold, structue-activity relationship, pharmacokinetics, overview	Rattus norvegicus

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
lysosome	-	Rattus norvegicus	5764	-

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	male Wistar rats	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
B-cell	-	Rattus norvegicus	-
dendritic cell	-	Rattus norvegicus	-
macrophage	-	Rattus norvegicus	-
additional information	the enzyme is expressed in antigen presenting cells	Rattus norvegicus	-

Synonyms

Synonyms	Comment	Organism
Cat S	-	Rattus norvegicus

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Release 2023.1 (January 2023)