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Literature summary for 3.4.22.27 extracted from

  • Kirschke, H.; Schmidt, I.; Wiederanders, B.
    Cathepsin S. The cysteine proteinase from bovine lymphoid tissue is distinct from cathepsin L (EC 3.4.22.15) (1986), Biochem. J., 240, 455-459.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.27

Inhibitors

Inhibitors Comment Organism Structure
Benzyloxycarbonyl-Phe-Phe-CHN2 0.0005 mM: 51-58% inhibition after 10 min. 0.005 mM: 86-90% inhibition after 10 min Bos taurus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.042
-
 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin pH 5.5, 30°C Bos taurus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
24000
-
 x * 24000, SDS-PAGE Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
lymphoid tissue
-
 Bos taurus
-
spleen
-
 Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Lys-4-nitrophenyl ester + H2O
-
 Bos taurus benzyloxycarbonyl-Lys + 4-nitrophenol
-
 ?
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O
-
 Bos taurus benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin
-
 ?

Subunits

Subunits Comment Organism
? x * 24000, SDS-PAGE Bos taurus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
7
-
 benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin pH 5.5, 30°C Bos taurus