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Literature summary for 3.4.22.27 extracted from

  • Shindo, K.; Suzuki, H.; Okuda, T.
    Paecilopeptin, a new cathepsin S inhibitor produced by Paecilomyces carneus (2002), Biosci. Biotechnol. Biochem., 66, 2444-2448.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
E64 64 nM Homo sapiens
leupeptin 5.2 nM Homo sapiens
paecilopeptin i.e. acetyl-Leu-Val-CHO, IC50: 21 nM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Val-Val-Arg-7-amido-4-methylcoumarin + H2O
-
Homo sapiens benzyloxycarbonyl-Val-Val-Arg + 7-amino-4-methylcoumarin
-
?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.000021
-
i.e. acetyl-Leu-Val-CHO, IC50: 21 nM Homo sapiens paecilopeptin