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Literature summary for 3.4.22.24 extracted from
- Purification and characterization of a new thiol proteinase from rat kidney (1981), Biochim. Biophys. Acta, 659, 114-122.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| sulfhydryl compounds | activation | Rattus norvegicus |  |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Oxidized ribonuclease A | tyrosine aminotransferase as substrate | Rattus norvegicus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| soluble | - |
Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 33500 | - |
gel filtration | Rattus norvegicus |
| 33500 | - |
kidney | Rattus norvegicus |
| 33500 | - |
rat, liver | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
albino male Holtzman rats | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Rattus norvegicus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| kidney | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| kidney | - |
Rattus norvegicus | - |
| liver | - |
Rattus norvegicus | - |
| lung | - |
Rattus norvegicus | - |
| additional information | tissue distribution, no activity in heart, skeletal muscle, brain and blood | Rattus norvegicus | - |
| small intestine | - |
Rattus norvegicus | - |
| spleen | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Acid-denatured hemoglobin + H2O | - |
Rattus norvegicus | ? | - |
? | |
| azocasein + H2O | - |
Rattus norvegicus | ? | - |
? | |
| Tyrosine aminotransferase form I + H2O | dimer of MW 52000 subunits | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | enzyme form II: dimer of MW 53000 + MW 49000, enzyme form III: dimer of MW 48000 | ? | |
| Tyrosine aminotransferase form I + H2O | from rat liver cytosol | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | enzyme form II: dimer of MW 53000 + MW 49000, enzyme form III: dimer of MW 48000 | ? | |
| Tyrosine aminotransferase form I + H2O | thereby generating multiple forms of tyrosine aminotransferase | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | enzyme form II: dimer of MW 53000 + MW 49000, enzyme form III: dimer of MW 48000 | ? | |
| Tyrosine aminotransferase form I + H2O | i.e. L-tyrosine:2-oxoglutarate aminotransferase or EC 2.6.1.5 | Rattus norvegicus | Tyrosine aminotransferase form II and III + acidic peptide of MW 4500 peptide | enzyme form II: dimer of MW 53000 + MW 49000, enzyme form III: dimer of MW 48000 | ? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | SDS-PAGE | Rattus norvegicus |
| monomer | kidney | Rattus norvegicus |
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