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Literature summary for 3.4.22.2 extracted from

  • Brocklehurst, K.; Baines, B.S.; Kierstan, M.P.J.
    Papain and other constituents of Carica papaya L (1981), Top. Enzyme Ferment. Biotechnol., 5, 262-335.
No PubMed abstract available

Application

Application Comment Organism
medicine used in external treatment of hard tissue, wart and scar tissue removal, acne treatment, depilation, skin cleansing treatment, inclusing in toothpaste. Papain is used in preparation of Tyr derivatives which are used for treatment of Parkinsonism and for the preparation of tetanus vaccines and immunoglobulin samples for intravenous injection Carica papaya
nutrition papain is used in the preparation of fish protein concentrates from fish waste Carica papaya
nutrition used in the tenderisation of meat by its action on connective tissue and muscle protein. Beef is the only meat that is routinely subjected to papain tenderisation and the application of this technology is almost exclusively restricted to the USA Carica papaya
nutrition the enzyme is used for the development of roast beef-like flavours by partial hydrolysis of proteins Carica papaya
nutrition production of dehydrated pulses and beans Carica papaya

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
20700
-
enzyme from commercial chymopapain, equilibrium measurement Carica papaya
23406
-
x * 23406, calculation from amino acid sequence Carica papaya
23800
-
enzyme from spray-dried latex, equilibrium measurement Carica papaya

Organism

Organism UniProt Comment Textmining
Carica papaya
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification propapain is a thio-containing but catalytically inactive protein, that is a structural isomer of papain that can be transformed into papain by thiol-disulfide interchange initiated by addition of a suitable nucleophile such as thiolate Carica papaya

Purification (Commentary)

Purification (Comment) Organism
-
Carica papaya

Source Tissue

Source Tissue Comment Organism Textmining
latex
-
Carica papaya
-

Subunits

Subunits Comment Organism
? x * 23406, calculation from amino acid sequence Carica papaya