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Literature summary for 3.4.22.2 extracted from
- The cysteine proteinases (1976), Tetrahedron, 32, 291-302.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Chloroacetate | - |
Carica papaya |  |
| iodoacetic acid | - |
Carica papaya | |
| L-Ala-L-Phe-aminoacetonitrile | - |
Carica papaya | |
| N-benzyloxycarbonyl-L-Phe-L-Ala chloromethyl ketone | - |
Carica papaya | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Carica papaya | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| side-chain modification | propapain is activated by intramolecular thiol-disulfide exchange which is catalyzed by cysteine | Carica papaya |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| latex | - |
Carica papaya | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Glucagon + H2O | - |
Carica papaya | ? | - |
? | |
| Hemoglobin + H2O | alpha-chain and beta-chain | Carica papaya | ? | - |
? | |
| oxidized beta-chain of insulin + H2O | - |
Carica papaya | ? | - |
? | |
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Release 2023.1 (January 2023)
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