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Literature summary for 3.4.22.2 extracted from

  • Rudolf, B.; Salmain, M.; Martel, A.; Palusiak, M.; Zakrzewski, J.
    eta(1)-N-succinimidato complexes of iron, molybdenum and tungsten as reversible inhibitors of papain (2009), J. Inorg. Biochem., 103, 1162-1168.
    View publication on PubMed
Search for more literature for 3.4.22.2

Inhibitors

Inhibitors Comment Organism Structure
(eta5-C5H5)Fe(CO)3 eta1-N-succinimidato metallocarbonyl complex, reversible inhibitor Carica papaya
(eta5-C5H5)Mo(CO)3 eta1-N-succinimidato metallocarbonyl complex, reversible inhibitor Carica papaya
(eta5-C5H5)W(CO)3 eta1-N-succinimidato metallocarbonyl complex, reversible inhibitor Carica papaya

Organism

Organism UniProt Comment Textmining
Carica papaya
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Pro-L-Phe-L-Leu-4-nitroanilide + H2O
-
 Carica papaya L-Pro-L-Phe-L-Leu + 4-nitroaniline
-
 ?

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.28
-
 pH 6.5, temperature not specified in the publication Carica papaya (eta5-C5H5)Mo(CO)3 eta1-N-succinimidato
0.48
-
 pH 6.5, temperature not specified in the publication Carica papaya (eta5-C5H5)W(CO)3 eta1-N-succinimidato
1.7
-
 pH 6.5, temperature not specified in the publication Carica papaya (eta5-C5H5)Fe(CO)3 eta1-N-succinimidato