Inhibitors | Comment | Organism | Structure |
---|---|---|---|
E-64 | irreversible active site inhibitor | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Arg-7-amido-4-methylcoumarin + H2O | - |
Mus musculus | L-Arg + 7-amino-4-methylcoumarin | - |
? | |
pro-granzyme B + H2O | cathepsin H has pro-granzyme B convertase activity in vitro | Mus musculus | granzyme B + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CatH | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
malfunction | lymphocytes deficient in CatH are still capable of generating active granzyme B. CatH-deficient mice do not show a gross morphological phenotype and no impairment of reproductive capacity or breeding behavior or nursing | Mus musculus |