Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.22.16 extracted from

  • Willenbrock, F.; Brocklehurst, K.
    Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe (1985), Biochem. J., 85, 511-519.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
2,2'-dipyridyl disulfide thiol-specific two-protonic-state reactivity probe Bos taurus

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Bos taurus

Reaction

Reaction Comment Organism Reaction ID
Hydrolysis of proteins, acting as an aminopeptidase (notably, cleaving Arg-/- bonds) as well as an endopeptidase mechanism: interactive catalytic-site system in which the nucleophilic character of the sulphur atom is maintained in acidic media Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
spleen
-
Bos taurus
-

Storage Stability

Storage Stability Organism
4°C, 0.02 M Na-acetate buffer, pH 5.0, 0.15 mM NaCl Bos taurus

pH Stability

pH Stability pH Stability Maximum Comment Organism
8.2
-
stable at 25°C, unstable at 37°C Bos taurus