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Literature summary for 3.4.22.15 extracted from

  • Wang, Y.R.; Qin, S.; Han, R.; Wu, J.C.; Liang, Z.Q.; Qin, Z.H.; Wang, Y.
    Cathepsin L plays a role in quinolinic acid-induced NF-?b activation and excitotoxicity in rat striatal neurons (2013), PLoS ONE, 8, e75702.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.22.15

Inhibitors

Inhibitors Comment Organism Structure
1-naphthalenesulfonyl-Ile-Trp-CHO reversible inhibitor of cathepsin L Rattus norvegicus
benzyloxycarbonyl-Phe-Phe-fluoromethylketone
-
 Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
striatal neuron
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-acetyl-Phe-Arg-7-amido-4-trifluoromethylcoumarin + H2O
-
 Rattus norvegicus N-acetyl-Phe-Arg + 7-amino-4-trifluoromethylcoumarin
-
 ?

General Information

General Information Comment Organism
physiological function cathepsin L plays a role in glutamate receptor-induced nuclear factor-kappa B activation and excitotoxicity in rat striatal neurons Rattus norvegicus