Literature summary for 3.4.22.15 extracted from

Pietra, D.; Borghini, A.; Ricci, C.; Bianucci, A.M.
Enzyme kinetics studies on 29-kDa human liver cathepsin L (2014), Chem. Biol. Drug Des., 84, 648-658.

Search for more literature for 3.4.22.15

General Stability

General Stability	Organism
when no reducing agents are present in the assay environment, the activity of cathepsin L is markedly slowed down, and the rate of product formation is reduced by about half	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
cystatin B	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
25000	-	1 * 25000 + 1 * 5000, SDS-PAGE	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P07711	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O	-	Homo sapiens	benzyloxycarbonyl-Phe-Arg + 7-amino-4-methylcoumarin	-	?

Subunits

Subunits	Comment	Organism
heterodimer	1 * 25000 + 1 * 5000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
CatL	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)