Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | under moderate hypoxic conditions of 1% O2, intracellular expression of cathepsin L is up-regulated. Hypoxia significantly increases only the expression of the transcript which contains the complete internal ribosome entry site, but inhibits promoter activity | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | in vivo a tumor hypoxic environment up-regulates cathepsin L expression which promotes tumor progression | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-375SM cell | - |
Homo sapiens | - |
DM-4 cell | - |
Homo sapiens | - |
melanoma cell | - |
Homo sapiens | - |
NCI-H1299 cell | - |
Homo sapiens | - |