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Literature summary for 3.4.22.15 extracted from
- Cathepsin L, but not cathepsin B, is a potential kininogenase (2001), Biol. Chem., 382, 811-815.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cystatin | from chicken, activity with benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin | Homo sapiens | |
| E-64 | activity with benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| kininogen + H2O | Homo sapiens | high and low molecular weight kininogen | kinin + ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| benzyloxycarbonyl-Phe-Arg-7-amido-4-methylcoumarin + H2O | - |
Homo sapiens | ? | - |
? | |
| kininogen + H2O | high and low molecular weight kininogen | Homo sapiens | kinin + ? | - |
? | |
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